News
New publication - Daniel C. Devor, Ph.D.
Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121. Kolski-Andreaco A, Taiclet S, Myerburg MM, Sembrat J, Bridges RJ, Straub AC, Wills ZP, Butterworth MB, Devor DC. J Clin Invest. 2024 Jul 2;134(16):e176328. doi: 10.1172/JCI176328.…
New publication - Yang Hong, Ph.D.
PI4P-mediated solid-like Merlin condensates orchestrate Hippo pathway regulation. Science 385:6709 Aug 2024
DOI: 10.1126/science.adf4478
New Grants - Daniel Devor, Ph.D.
8/1/2024 - 4/30/2028
Award # : RO1HL171413
Agency: NIH
Title: Modulation of Ca2+ -activated K+ channels by CFTR Correctors
New publication - Tarique Bagalkot
Bagalkot, T., and Sorkin, A. (2023) Amphetamine induces sex-dependent loss of the striatal dopamine transporter in sensitized mice. eNeuro ENEURO.0491-23.2023; DOI: 10.1523/ENEURO.0491-23.2023
New publication - Itziar Pinilla-Macau
Pinilla-Macua, I., and Sorkin, A. (2023) Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes. Mol. Biol. Cell. doi.org/10.1091/mbc.E23-02-0058.
New grant - Claire Weckerly
8/1/23-7/31/26
Award Number - F31HL170755-01
Title - The roles of PLD and DGK isoforms in PIP2 homeostasis during PLC signaling
Agency - National Heart, Lung, and Blood Institute
New grant - Sahana Balasubramanian
6/1/23-5/31/25
Award Program Type: Predoctoral Fellowship
Title of Project: Extracellular matrix driven changes in cardiomyocyte organization and adhesion
AHA Award Number: 1029027
New publication - Deepika Vasudevan, Ph.D.
Shyam R, Shu DY, Zuniga-Sanchez E, Vasudevan D. Editorial: Molecular mechanisms in ocular development and disease.. Front Cell Dev Biol. 2023;11():1244123. doi: 10.3389/fcell.2023.1244123. PubMed PMID: 37457294;
New publication - Karina J Vargas, Ph.D.
Vargas KJ, Colosi PL, Girardi E, Park JM, Harmon LE, Chandra SS. α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices.. J Biol Chem. 2023 Jul 27;():105091. doi: 10.1016/j.jbc.2023.105091. PubMed PMID: 37516240;
New grant - Lydia Grmai, Ph.D.
K99 NIGMS (NIH)
Title: "Integrated stress response signaling as a metabolic sensor for reproduction"
Years: 2023-2028
Co-sponsors: Deepika Vasudevan, PhD (Pitt); Kafui Dzirasa, MD, PhD (Duke University)
New grant - Deepika Vasudevan, Ph.D.
9/13/23-7/31/28
Award #: R35GM150516
Agency: NIGMS
Title: Elucidating the role of the Integrated Stress Response pathway in tissue homeostasis
New publication - Gerry Hammond, Ph.D.
Ricci MMC, Orenberg A, Ohayon L, Gau D, Wills RC, Bae Y, Das T, Koes D, Hammond GRV, Roy P. Actin-binding protein profilin1 is an important determinant of cellular phosphoinositide control.. J Biol Chem. 2023 Dec 21;300(1):105583. doi: 10.1016/j.jbc.2023.105583. PubMed PMID: 38141770
New publication - Gerry Hammond, Ph.D.
Doyle CP, Rectenwald A, Timple L, Hammond GRV. Orthogonal targeting of SAC1 to mitochondria implicates ORP2 as a major player in PM PI4P turnover.. bioRxiv. 2024 Jan 11;():. pii: 2023.08.28.555163. doi: 10.1101/2023.08.28.555163. PubMed PMID: 37693626;